Multi Cycle Cell Disruptor – High pressure homogeniser for all types of cell suspensions

The new Multi Cycle model (former Multi Shot) from Constant Systems bridges the gap between the One Shot and continuous flow models – it is an excellent high pressure homogeniser for all types of cell suspensions, for volumes of 1-80 ml. It is able to continuously process 40 ml of sample, by firing 5 shots of 8 ml, without requiring manual reloading.

During the shot, the piston forces the sample through the fixed orifice into the receiving cup, thereby disrupting the cells. The Multi Cycle Cell Disruptor offers a well-priced alternative to the continuous flow machines for all users with a sample volume below 100 ml. As on the One Shot, the removable parts are made of stainless steel, which can be pre-cooled on ice, or the whole system can be placed in a cold room.

The Multi Cycle can also homogenise in the single shot mode, in the same manner as the One Shot, enabling it to process samples in any state (including viscous, pellet/paste, solid tissue and frozen sample).

Technical data



Process volume 1-40 mL (max 80 mL)
Dead volume 0.1 mL
Cycles up to 5
Pressure up to 2700 bar (40.000 PSI)
Sample type liquid, solid, frozen, paste, pellet
Fixed orifice yes
Sample cooling no
Compressed air required no
Dimensions (H x W x D) 51 x 47.5 x 50 cm
Weight 110 kg


Technical Service

During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.

Detailed information about our support options can be found here.

Logo Constant Systems
Constant Systems Ltd.

Constant Systems Limited was established in 1989 and manufactures und designs high pressure cell disruption equipment. The company has been committed to the design, development, manufacture and aftermarket support of cell disruption equipment, and the hard work and dedication makes it the first-choice supplier for Pharmaceutical/Biotech companies, Research Institutes, Universities and Schools worldwide. Their equipment is used in drug discovery, protein characterization and functional studies of cellular processes. To date, the products of Constant Systems have directly contributed to research published in over 2,000 peer reviewed papers across a range of academic journals, including Nature and the Journal of Biological Chemistry.

More about Constant Systems: https://constantsystems.com/


Do you have any further questions and would like to be informed? We will be glad to help you!

Your contact data

* required infos

Your contact person

No person found
125 employees
10 locations in europe
32 years of experience