SuperFlo® Production Chromatography Column
Low pressure production chromatograpy columns
SuperFlo® Radial Flow Chromatography Columns are redefining the possibilities in low pressure, preparative liquid chromatography. Due to the unique design, the column offers a significantly larger sample inlet area, which results in lower linear velocities, even at high total flow rates. The production columns are available from 5-500 L made from acrylic or stainless steel. SuperFlo® chromatography columns for laboratories in sizes from 50-1500 ml can be found here.
- Offers high flow rates
- Low working backpressures
- Fast separations
- Ideal for antibody purification
- Easy and fast to pack
- Worldwide in use for plasma fractionation
- Antibody Purification
- Process Chromatography
- Great Britain
SuperFlo® Production Chromatography Column
The SuperFlo® column consists of two concentric porous cylinders, creating a space. This area between the frits is the column bed and this is packed with the chromatographic resin. The eluent/sample enters at the top of the column, the top lid acts as a distribution head and directs the sample into the gap between the outer column body and the outer frit. It distributes over the whole height of the column and flows horizontal from the outer frit to the inner core. From the gap between the inner frit and the collector rod (spacer in the centre of the column) the eluent leaves through the outlet at the bottom of the column. The effective bed height of the column is the distance between inner and outer frit.
The intrinsic design of the SuperFlo® column has a significantly larger surface area than a tradtional axial column, therefore even at high flow rates the linear velocity is in a range which allows for the required interaction between sample and resin. SuperFlo® allows to make your separation faster and in certain cases you can save expensive resin (e.g. Protein G) because you can make 2 runs in the same time - means you can reduce the size of the column by 50%. The investment into a SuperFlo® column will be compensated by the savings in resin costs after the first column packing.
Sepragen SuperFlo | Radial flow chromatography column | Pt.1
Sepragen SuperFlo | Radial flow chromatography column | Pt.2
Sepragen SuperFlo | Radial flow chromatography column | Pt.3
|Production SuperFlo column||Bed height|
|Lab columns 50-1500 ml||3.5 cm|
|5 and 10 L||5 cm|
|20 - 100 L||10 cm|
|up to 500 L||15 or 20 cm|
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.
The Sepragen Corporation is based in Union City, California, and provides break-through products and processes to the biotechnology and nutraceutical industries for their process development and manufacturing needs. The company's products enable their customers several fold higher productivity in a smaller footprint, ease of use and rapid, predictable scale up of processes from the laboratory to production. This results in lower capital outlay, lower cost of goods and rapid time to market. All products are designed and manufactured to the highest standards of quality and with the standards of traceability and cGMP compliance.
More about Sepragen: www.sepragen.com
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