Use of Pu•MA System™3D for automated media and compound treatment along with in situ lysing of spheroids for metabolomics. The ability to lyse organoids in situ in order to capture metabolomic profiles with minimal disruption of the spheroids shows great promise for research. All reagents are loaded into flow chips and then incubation, media exchanges, cell secretion sampling and other steps are executed by the system program with a recovery rate of up to 95% without drying cells.
Interested? Learn more about this in our free App Note "Use of Pu•MA System™ 3D for Single Spheroid Assays with Downstream Metabolomics"