Biolayer interferometry (BLI) is a label-free biosensing method that is widely used to study biomolecular interactions. Created by GatorBio co-founder Hong Tan, BLI measures the interference pattern of white light that is reflected from the surface of a biosensor. Binding of biomolecules to the sensor surface is measured as interference shift and recorded in real-time to determine kinetic association and dissociation rates between molecular interaction pairs with high precision. The most common applications for BLI are biomolecular quantitation and analysis of intermolecular interactions (Kd, kon, koff).
With the GatorPrime and GatorPlus, the original inventors of the BLI technology share their vision to: “Empower researchers by creating a more powerful, productive and cost-effective BLI system” and introduce the next-generation of BLI instruments to the scientific community.