[Translate to EN:] Fluxion Biosciences BioFlux 1000Z

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Fluxion Biosciences

BioFlux™ 1000Z

Live cell assays under shear flow

The BF1000 has been developed to perform flow-based assays automatically at high throughput rates. The BF1000Z consists of the BioFlux controller and a Zeiss microscope. The screw cap of the BioFlux Interface has been replaced by a faster clip cap on the BF1000Z and there is a comprehensive integrated flow control and analysis package.

Up to 96 flow experiments in parallel
Precise shear force control (0.2 - 200 dyne)
Pulsative flow up to 75 x / min
Including Zeiss microscope with individual equipment
Software for automatic flow control and automatic image evaluation
Applications: Platelet aggregation, biofilm, cell adhesion...

3D Cell Culture
Bacteria Cultivation
Microscopy
Cell Culture
Microbiology
Cell Biology

Germany
France
Austria

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BioFlux™ 1000Z

The BioFlux™ 1000 system is designed for automated live cell imaging analysis under physiological and pathophysiological flow conditions (from 0.2 - 200dyne). The applications are versatile and range from analysis of platelet aggregation, cell adhesion, migration, transmigration, wound healing, stem cell differentiation to biofilm analysis, inhibition studies and host-pathogen interactions.

The use of microtiter plates with integrated microfluidics combines the simplicity and high throughput of corrugated plates with the quality and relevance of flow experiments. Thus it is possible to perform up to 96 live cell assays under controlled flow conditions in parallel.

In order to ensure the best possible optical properties, the bottom of the microtiter plates is made of optical glass. Furthermore, the BioFlux1000 instrument consists of the classic BioFlux instrument together with an automatic inverse Zeis microscope. Both systems are optimally matched to each other. This enables faster sample and experiment setup and automated data analysis. This allows fast and reproducible experiments even with high sample volumes and sensitive samples.

Technical data

Flow control	0.2 - 200 dyne
Temperature control	RT + 50°C
Microtiterplate	SBS Standard, sterile, with PDMS channels and glass bottom
Microtiter plate format	6-well for up to 3 experiments (1 inputs / channel)
	24-well for up to 8 experiments (2 inputs / channel)
	48-well for up to 24 experiments (1 input / channel)
Throughput	Up to 24 experiments in parallel with adapter up to 96 experiments
Dimension observation channel	350 µm x 70 µm (w x h)

BioFlux Controller dimension	30 x 33 x 23 cm
Weight Bioflux Controller	approx. 17 kg
Mikroscope	Zeis Z1 - individually equipped
Software	Montage, combines Flow and Microscope control and Data analysis

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Glass heating plate for Matrigel applications	Fluxion
24-well interface (clip closure)	Fluxion
48-well interface (clip closure)	Fluxion
Pulsative flow	Fluxion

Technical Service

During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.

Detailed information about our support options can be found here.

Fluxion Biosciences

Fluxion Biosciences is located in California and delivers advanced solutions that automate complex cell-based and cell-free assays. Products include ERASE-Seq for NGS analysis of cancer from a "liquid biopsy"blood sample, IsoFlux for circulating tumor cell analysis, BioFlux for functional analysis of cellular interactions, and the IonFlux automated patch clamp system. Hundreds of labs worldwide rely on Fluxion's solutions to research novel biology, accelerate drug discovery, and tailor therapies based on patient-specific biomarkers.

More about Fluxion Biosciences: www.fluxionbio.com

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125 employees

10 locations in europe

31 years of experience

BioFlux™ 1000Z

Live cell assays under shear flow

Technical data

Downloads

Brochures

Manuals

Consumables

Technical Service

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