Live cell assays under shear flow
The BF1000 has been developed to perform flow-based assays automatically at high throughput rates. The BF1000Z consists of the BioFlux controller and a Zeiss microscope. The screw cap of the BioFlux Interface has been replaced by a faster clip cap on the BF1000Z and there is a comprehensive integrated flow control and analysis package.
- Up to 96 flow experiments in parallel
- Precise shear force control (0.2 - 200 dyne)
- Pulsative flow up to 75 x / min
- Including Zeiss microscope with individual equipment
- Software for automatic flow control and automatic image evaluation
- Applications: Platelet aggregation, biofilm, cell adhesion...
- 3D Cell Culture
- Bacteria Cultivation
- Cell Culture
- Cell Biology
The BioFlux™ 1000 system is designed for automated live cell imaging analysis under physiological and pathophysiological flow conditions (from 0.2 - 200dyne). The applications are versatile and range from analysis of platelet aggregation, cell adhesion, migration, transmigration, wound healing, stem cell differentiation to biofilm analysis, inhibition studies and host-pathogen interactions.
The use of microtiter plates with integrated microfluidics combines the simplicity and high throughput of corrugated plates with the quality and relevance of flow experiments. Thus it is possible to perform up to 96 live cell assays under controlled flow conditions in parallel.
In order to ensure the best possible optical properties, the bottom of the microtiter plates is made of optical glass. Furthermore, the BioFlux1000 instrument consists of the classic BioFlux instrument together with an automatic inverse Zeis microscope. Both systems are optimally matched to each other. This enables faster sample and experiment setup and automated data analysis. This allows fast and reproducible experiments even with high sample volumes and sensitive samples.
|Flow control||0.2 - 200 dyne|
|Temperature control||RT + 50°C|
|Microtiterplate||SBS Standard, sterile, with PDMS channels and glass bottom|
|Microtiter plate format||6-well for up to 3 experiments (1 inputs / channel)|
|24-well for up to 8 experiments (2 inputs / channel)|
|48-well for up to 24 experiments (1 input / channel)|
|Throughput||Up to 24 experiments in parallel with adapter up to 96 experiments|
|Dimension observation channel||350 µm x 70 µm (w x h)|
|BioFlux Controller dimension||30 x 33 x 23 cm|
|Weight Bioflux Controller||approx. 17 kg|
|Mikroscope||Zeis Z1 - individually equipped|
|Software||Montage, combines Flow and Microscope control and Data analysis|
[Translate to EN:] BioFlux Overview1.72 MB
[Translate to EN:] BF Comparision Chart106.81 KB
[Translate to EN:] BioFlux1000 TechnicalData30.87 KB
[Translate to EN:] BiofilmGrowth316.14 KB
[Translate to EN:] Cancer cell adhesion assay557.52 KB
[Translate to EN:] Cellular Monolayer in microfluidic channels1.81 MB
[Translate to EN:] Cell rolling357.23 KB
[Translate to EN:] Host Pathogen Interactions1.93 MB
[Translate to EN:] Matrigel in Microfluidic channels95.77 KB
[Translate to EN:] Platelet Adhesion and Aggregation Assay643.01 KB
[Translate to EN:] Platelet Adhesion dose rsponsen708.04 KB
[Translate to EN:] Pulsatile Flow Module - Tech Note (1075-01)177.95 KB
[Translate to EN:] StemCell Differentiation2.92 MB
[Translate to EN:] Transmigration711.01 KB
[Translate to EN:] Wound Healing1.11 MB
|Glass heating plate for Matrigel applications||Fluxion|
|24-well interface (clip closure)||Fluxion|
|48-well interface (clip closure)||Fluxion|
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.
Fluxion Biosciences is located in California and delivers advanced solutions that automate complex cell-based and cell-free assays. Products include ERASE-Seq for NGS analysis of cancer from a "liquid biopsy"blood sample, IsoFlux for circulating tumor cell analysis, BioFlux for functional analysis of cellular interactions, and the IonFlux automated patch clamp system. Hundreds of labs worldwide rely on Fluxion's solutions to research novel biology, accelerate drug discovery, and tailor therapies based on patient-specific biomarkers.
More about Fluxion Biosciences: www.fluxionbio.com
Also interesting for you
InvivO₂® 300 Hypoxia Workstation
With Baker Ruskinns InvivO₂® 300 hypoxic chamber you can study even the most complex cell interactions under perfect hypoxic or anoxic conditions: The workstation provides accurate, stable, and user-defined oxygen, carbon dioxide, temperature and humidity control, creating the optimal environment for cell culture and translational research.Learn more
Fluxion's BioFlux™ 200 system enables cell-based assays to be performed under physiological flow conditions. The use of microplates with integrated microfluidics combines the simplicity and high throughput of microplates with the quality and relevance of flow experiments.Learn more