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Fluxion Biosciences
BioFlux™ 200
Live cell assays under shear flow
Fluxion's BioFlux™ 200 system enables cell-based assays to be performed under physiological flow conditions. The use of microplates with integrated microfluidics combines the simplicity and high throughput of microplates with the quality and relevance of flow experiments.
- Up to 96 flow experiments in parallel
- Precise shear force control (0.2 - 200 dyne)
- Pulsative flow up to 75x / min
- Automatic flow control (with changing conditions)
- Glass bottom for optimal microscopic images
- Applications: Platelet aggregation, biofilm, cell adhesion
- 3D Cell Culture
- Bacteria Cultivation
- Microscopy
- Cell Culture
- Microbiology
- Cell Biology
- Germany
- France
- Austria
BioFlux™ 200
The BioFlux™ 200 system has been developed for live cell imaging analysis under physiological and pathophysiological flow conditions (from 0.2 - 200 dyne). The applications are versatile and range from analysis of platelet aggregation, cell adhesion, migration, transmigration, wound healing, stem cell differentiation to biofilm analysis, inhibition studies and host-pathogen interactions.
The use of microtiter plates with integrated microfluidics combines the simplicity and high throughput of well plates with the quality and relevance of flow experiments. Thus it is possible to perform up to 96 live cell assays under controlled flow conditions in parallel. In order to ensure the best possible optical properties, the bottom of the microtiter plates is made of optical glass. Furthermore, the BioFlux™ 200 instrument is compatible with inverted microscopes and the microtiter plates are suitable for fluorescence, phase contrast or confocal imaging. The included software automates the experimental setup and provides versatile analysis options.
Fluxion Biosciences | BioFlux 200 | Live cell assays under shear flow
Technical data
| Flow control | 0.2 - 200 dyne |
| Temperature control | RT + 50°C |
| Microtiterplate | SBS Standard, sterile, with PDMS channels and glass bottom |
| Microtiter plate format | 6-well for up to 3 experiments (1 inputs / channel) |
| 24-well for up to 8 experiments (2 inputs / channel) | |
| 48-well for up to 24 experiments (1 input / channel) | |
| Throughput | Up to 24 experiments in parallel with adapter up to 96 experiments |
| Dimension observation channel | 350 µm x 70 µm (w x h) |
| Controler dimension | 30 x 33 x 23 cm |
| Weight | approx. 17 kg |
| Mikroscope | not included - compatible with inverted microscopes with a working distance of minimum 5 cm between table + condenser |
Downloads
Brochures
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BF200 Data Sheet276.21 KB
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BF Comparision Chart106.81 KB
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BF EZ Data Sheet204.10 KB
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BioFlux200 TechnicalData30.28 KB
Manuals
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BiofilmGrowth316.14 KB
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BioFlux Overview1.72 MB
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Cancer cell adhesion assay557.52 KB
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Cellular Monolayer in microfluidic channels1.81 MB
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Cell rolling357.23 KB
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Host Pathogen Interactions1.93 MB
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Matrigel in Microfluidic channels95.77 KB
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Platelet Adhesion and Aggregation Assay643.01 KB
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Platelet Adhesion dose rsponsen708.04 KB
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Pulsatile Flow Module - Tech Note (1075-01)177.95 KB
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StemCell Differentiation2.92 MB
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Transmigration711.01 KB
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Wound Healing1.11 MB
Consumables
| Glass heating plate for Matrigel applications | Fluxion |
| 24-well interface (screw or clip cap) | Fluxion |
| 48-well interface (screw or clip closure) | Fluxion |
| Pulsative flow | Fluxion |
Technical Service
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.
Fluxion Biosciences is located in California and delivers advanced solutions that automate complex cell-based and cell-free assays. Products include ERASE-Seq for NGS analysis of cancer from a "liquid biopsy"blood sample, IsoFlux for circulating tumor cell analysis, BioFlux for functional analysis of cellular interactions, and the IonFlux automated patch clamp system. Hundreds of labs worldwide rely on Fluxion's solutions to research novel biology, accelerate drug discovery, and tailor therapies based on patient-specific biomarkers.
More about Fluxion Biosciences: www.fluxionbio.com
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