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Cedex HiRes® – Cell culture analyzer and cell counter

The Cedex® HiRes Analyzer features high-resolution, scanner-based imaging that enables deeper insights into even subtile changes in your cell culture. The Cedex® HiRes Analyzer offers precise cell counting and state-of-the-art automation by combining the Trypan Blue exclusion method and CCD scanner capturing high-resolution digital images across the sample in the whole flow chamber. The analyzer not only measures cell concentration and cell viability but also morphological parameters such as cell diameter and compactness, and provides quantitative information about cell aggregation in cell containing samples.

 

The Cedex® Software features Live Operator for real-time optimization of the analysis algorithm, and a Cultivation Time Chart for monitoring cell growth to determine growth rates and doubling times. In combination with the Cedex® Bio HT, the Cedex® HiRes can be integrated into fully automated process systems. The Cedex® HiRes can be used in GMP-validated biopharmaceutical production processes and conforms to GMP regulations, such as 21 CFR part 11.

Are you interested in automating the data handling of your Cedex® instrument? Then have a look at Sm@rtLine Data Cockpit (SDC) from our partner AGU. SDC is a middleware for central data handling in production, development and research and enables the connection of the Cedex instruments (and many more analyzers) to your LIMS system.

Contact us to figure out if SDC is the solution to your requirements.

Technical data

 

 

Method of Measurement

High-resolution scanner technology
Digital image recognition
Complete flow chamber check for full transparency of cell culture analysis

Detectable Range

Objects: 1 - 70 µm
Cell diameter 2- 40 μm

Detectable Cell Density 5 x 104 - 1 x 107 cells/mL
Sample Volume 300 µl 
Sample Input  Integrated High-Speed Multi Sampler for single samples and multiple runs
Maintenance Automated cleaning and maintenance procedures
Software Features

Diameter Histogram showing cell size distribution
Aggregate Histogram showing cell culture aggregation state
Compactness Histogram depicting cell morphology
User roles easily created for multiple or single users

Live Operator

High-speed real-time parameter optimization for specific cell lines
Customized analysis of acquired images

Database filter chart

Stores all results and images
Measurement results easily found using searchable directory

Operating Conditions 

Temperature: +10 to +40°C (optimal  +20 to +30°C)
Humidity: 20-80% relative humidity (non-condensing)

Electrical Requirements  

Power requirements: 100 - 250 V AC
Consumption: 60 W
Frequency: 50 Hz - 60 Hz

Physical Dimensions  

Width: 405 mm
Depth: 535mm 
Height: 465 mm
Weight: 26,9 kg

Certificates  Audit trail for 21 CFR part 11 compliance

 

Consumables

 

 

Cedex HiRes Reagent Kit Art. no.: RD-05650798001
PU: 1 pack (Ca. 100 100 measurements)
Cedex HiRes Trypan Blue Re-fill Art. no.: RD-05650640001
PU: 4x 60 mL
Cedex HiRes Cleaning Re-fill Art. no.: RD-05650666001
PU: 4x 60 mL
Cedex HiRes Detergent Re-fill Art. no.: RD-05650658001
PU: 4x 60 mL
Cedex HiRes Detergent Art. no.: RD-05650496001
PU: 1000 mL
Cedex HiRes Calibration Beads Art. no.: RD-05650470001
PU: 20 mL
Cedex HiRes Control Beads 5*105 Art. no.: RD-05650780001
PU: 30 mL
Cedex HiRes Control Beads 1*106 Art. no.: RD-05650771001
PU: 30 mL
Cedex HiRes Control Beads 5*106 Art. no.: RD-05650763001
PU: 30 mL
Cedex HiRes Viability Beads 30% Art. no.: RD-05650704001
PU: 30 mL
Cedex HiRes Viability Beads 60% Art. no.: RD-05650712001
PU: 30 mL
Cedex HiRes Viability Beads 80% Art. no.: RD-05650739001
PU: 30 mL
Cedex HiRes Viability Beads 100% Art. no.: RD-05650747001
PU: 30 mL
Cedex HiRes Density Reference Standard Beads (DRSB) Batch A Art. no.: RD-06422659001
PU: 30 mL
Cedex HiRes Density Reference Standard Beads (DRSB) Batch B Art. no.: RD-06422667001
PU: 30 mL
Cedex HiRes Sample Cups Art. no.: RD-05650623001
PU: 500 pieces

 

Technical Service


During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.

Detailed information about our support options can be found here.

Logo Roche CustomBiotech
Roche CustomBiotech

Roche CustomBiotech provides reliable, tailored, and high-quality products and raw materials to Biopharma and Diagnostics companies. With the CustomBiotech division Roche merged its innovative technologies, excellent knowledge, and decades of experience in the Biopharma and Diagnostics Industry. Biopharma and Diagnostics customers get access to high-quality products, including solutions, raw materials, and instruments like the Cedex Analyzer Family. The products from Roche CustomBiotech are off the shelf or customizable to meet excellent quality and regulatory needs.

More about Roche CustomBiotech: https://custombiotech.roche.com

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125 employees
10 locations in europe
32 years of experience