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The next generation of Biolayer Interferometry (BLI) technology

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Gator Bio BLI system label free analysis
Gator Bio BLI system label free analysis

Improve your label-free analysis of biomolecular interactions with the newest innovations in BLI technology.

With the Gator Bio systems, the original inventors of the BLI technology introduce a new generation of more powerful, productive and cost-effective BLI instruments to the scientific community. The Gator Bio instruments offer an improved design, paired with the newest developments in biosensor technology. The improved thermal insulation of the optical bench leads to a more stable baseline, which helps while measuring long off-rates of tight binding interactions. A new generation of biosensors contain improved surface chemistry, which enhances their sensitivity, binding capacity, robustness and regeneration capability. The BLI technology from Gator Bio is flexible, highly-sensitive and accessible. From experiment to analysis, you can characterize the widest range of molecules on a single state-of-the-art platform - in a single run.
 

Key features of the Gator Bio system include:

  • Innovative Biosensors
  • Enhanced sensitivity
  • More stable baseline
  • Two-plate setup for increased sample capacity
  • Frequent releases of new and improved biosensors and kits

 

Accelerate your Antibody development Applications:

  • Rapid and easy quantitation of Antibody titer with wide dynamic range
  • High-throughput kinetic experiments to determine kon, koff and Kd of interaction pairs
  • 32 x 32 Epitope binning assay in 8 hours; Complete a 96 x 96 binning matrix in 5 days

 

Download Antibody Solution Application Note

Gator Bio BLI System 3D

More powerful

The next generation of BLI comes with the newest advancements in biosensor technology. The improved surface chemistry enhances the sensitivity of the sensors and increases the dynamic range in which they can measure. That means that you can quantify lower concentrations and resolve higher affinities with more precision. The prime example for this is the Small-Molecule-Analysis-Probe (SMAP), which redefines the limits of molecular weight that can be detected with BLI. Additionally, the research and development team at Gator Bio never stops to develop new and improved biosensors. This ensures, that you will be working with state-of-the-art technology for the long run.

first generation BLI system

Next geneartion BLI system

Kinetic characterization of Anti-fluoreszine and fluoreszine (332 Da). The innovative three-dimensional surface chemistry of the new SMAP biosensors drastically increases the binding capacity and thereby enhances sensitivity when working with biotinylated molecules.

Innovative Biosensors

Gator Bio's biosensors offer a unique advantage in expanding the range of detectable molecules in various applications. The high sensitivity of their SMAP probes enables the detection of low molecular weight targets, while the SA XT probes are specialized for higher molecular weight targets. This empowers you to work with a broad spectrum of molecules, ranging from small molecules to Lipid Nanoparticles or protein aggregates. Moreover, the company's commitment to innovation is evident through its R&D team, which is continuously developing new biosensors to keep customers at the forefront of label-free interaction analysis technology.

variety of available streptavidin probes

Best-in-class baseline stability

Long-term baseline stability is a key element when measuring slow dissociation rates. Gator Bios improved thermal insulation of the optical bench greatly reduces background noise which results in a clearer signal. This makes it possible to extend the measurement time in the dissociation step and to precisely measure high affinity interactions up to picomolar range. Accelerate your antibody discovery by identifying strong candidates early and with high accuracy.

 

 

Kinetic characterization of TNF-α and anti-TNF-α. A clean signal with little noise and minimal baseline drift enables extended off-rate measurements to determine picomolar interactions with high precision.

Gator Bio BLI system: Best-in-class baseline stability

More productive

For Gator Bio, the user experience is as important as the technical advantages. The two-plate design opens up space for your important samples. The Max plate can be filled up with sensors, wash- and regeneration-steps, while the second plate remains completely free for up to 96 samples. New biosensor technologies like the Flex SA Kit, which lets you reactivate and reuse your streptavidin, let you get more experiments done with less probes and increased walk-away times. This is complemented by an integrated user-friendly software that even unexperienced lab members will learn to easily operate in no time.

Gator Bio FLEX SA Kit

Gator Bio FLEX SA Kit

Gator Bio BLI System time

Kinetic characterization of TNF-α and anti-TNF-α for over 10 reactivations. The FLEX SA Kit lets you reactivate your Streptavidin sensors so you get more experiments done with less probes. The days of single use biosensors are over.

Cost effective

Gator Bios patented biosensor surface chemistry is more robust than ever before. This increases their regeneration capability, so you can save on cost with each sensor. You´ll get twenty experiments done for the price of one. Gator Bio strives to make BLI accessible for as many researchers as possible. That’s why the Gator Bio instruments are very affordable, not only for industry, but also for academic labs.

 

Do you think a state-of-the-art BLI system is too expensive for your lab? You will be surprised! Ask us for a quote on the instruments.
 

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First generation BLI mFc

mFc Gator Bio BLI System

Regeneration profile: Concentration series of mouse IgG (10 µg/ml - 0.1 µg/ml) measured 20 times with sensor regeneration. The improved biosensor surface chemistry allows for more regeneration cycles without a loss in binding capacity.

Additional features

  • Wide dynamic range: The improved biosensor surface chemistry increases the concentration range for quantitations
  • Unique applications: Quantify your AAV samples with the new ready-to-use AAVX-probes
  • User friendly: The intuitive software enables fast and easy assay setup and analysis - even for users with little experience
  • Customer support: Gator Bio listens to customer feedback and incorporates it into future releases and updates
  • Future prove: The frequent releases of new and improved biosensors ensure that your assays are always performed with state-of-the-art technology

Gator Bio Software

Accelerate your Antibody development Applications:

  • Rapid and easy quantitation of Antibody titer with wide dynamic range
  • High-throughput kinetic experiments to determine kon, koff and Kd of interaction pairs
  • 32 x 32 Epitope binning assay in 8 hours; Complete a 96 x 96 binning matrix in 5 days

 

Download Antibody Solution Application Note

Next generation of Biolayer Interferometry (BLI) Systems from Gator Bio

Gator Bio GatorPrime BLI system for AAV

 

GatorPrime

Next Gen label-free Biolayer interferometry (BLI) instrument

The GatorPrime is our entry level instrument that brings next generation BLI technology into your lab. This versatile 8-channel instrument uses our variety of new high-performance biosensors and is ideal for groups that are working on a budget.

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Gator Bio GatorPlus BLI system for AAV

GatorPlus

Next gen label-free BLI instrument with high sensitivity

The Gator Plus is our advanced 8-channel system that provides you with the additional option to use 384 well plates. Increase your run times and significantly reduce your sample volume while still getting the same high-quality data sets from our innovative biosensors.

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GatorPro

GatorPro

The most powerful BLI instrument in the world

The Gator Pro is our 32-channel system that puts high-throughput to the next level. Equipped to handle 3 x 384-well plates and ready for automation. Finish your 32 x 32 Epitope binning experiments in just 8 hours without suffering a loss in data quality.

 

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Gator Bio BLI system overview

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