Advanced Instruments
OsmoTECH® HT Osmometer
A 96-well Plate-Based High-Throughput Micro Osmometer
The OsmoTECH HT, is a plate-based micro-osmometer to support the growing automation and high throughput needs in bioprocessing. The instrument ensures efficiency and acceleration of osmolality testing in for example cell line development and formulation development. The 21 CFR part 11 compliant OsmoTECH HT provides intuitive workflows and delivers unsurpassed data management.
- Automation-friendly 96-well plate format
- Supports 21 CFR part 11 and GMP
- Reducing hands-on, automated cleaning
- User friendly interface
- OPC, USB, LIMS and network share connectivity
- Flexible and secure data management
More osmometers:
For Biotech: Also check out out the OsmoTECH PRO multi-sample osmometer. Looking for a single-sample osmometer? Check out the OsmoTECH and OsmoTECH XT. For Clinical Chemisty: Also check out the OsmoPRO and OsmoPRO MAX multi-sample osmometer. Looking for a single-sample osmometer? Check out the Osmo1.
- Cell Culture
- Good manufacturing practice (GMP)
- Automation
- Process Development
- Upstream
- Downstream
- Osmolality
- Belgium
- Denmark
- Netherlands
- Sweden
OsmoTECH HT – Osmometer for high sample throughput
The OsmoTECH HT was developed to meet the high throughput needs of cell line development, clone screening, and early process development. It incorporates freezing point depression technology to test osmolality and offers accuracy, precision, and ease-of-use.
The OsmoTECH HT is an automation-friendly, batch plate-based osmometer that offers these features to streamline sample testing while ensuring data integrity in all phases of the testing process:
- An easy-to-use, menu-driven touchscreen interface to access instrument features.
- Automated sample pipetting from a 96-well plate format to support your high-volume workflow, eliminating the need for time-consuming manual pipetting into wells and ensuring pipetting consistency.
- Reliable results using small sample sizes: Only 50 μL per plate well needed to run a standard sample test.
- Load up to two plates onto the instrument to perform 192 consecutive tests. The instrument can perform up to 1,000 tests before consumables need to be reloaded.
- Industry-standard support for interfacing with a local area network (LAN).
- Automated barcode reading of 96-well plates.
- Customized sampling templates.
Technical data
| Sample type | Aqueous-based solution |
| Sample volume | Minimum per well: 50 μl Maximum per well: 180 μl |
| Test time | 60 mins for 25 samples |
| 3 hr 40 mins for 96 well plate | |
| Sample format | 96-well plate |
| Resolution | 1 mOsm/kg H2O |
| Range (2) | 0-2000 mOsm/kg H2O |
| Accuracy (3) (AI standards and reference solutions) | Mean value ±3 mOsm/kg H2O from nominal value between 0 and 400 mOsm/kg H2O (1 SD) Mean value ±1% from nominal value greater than 400 to 2000 mOsm/kg H2O (1 SD) |
| Within-run repeatability (3) (AI standards and reference solutions) | Standard deviation ≤3 mOsm/kg H2O between 0 and 400 mOsm/kg H2O Coefficient of variation ≤1% greater than 400 to 2000 mOsm/kg H2O |
| Operating conditions | Temperature: 18 °C to 35 °C (64 °F to 95 °F) Humidity: 5 to 80% relative humidity (non-condensing) |
| Supported languages | Simple Chinese, English, French, German, Italian, Japanese, Korean, Portuguese, Russian, Spanish, Turkish |
| Storage temperature | -20 °C to +45 °C (-4 °F to +113 °F) |
| Electrical voltage | 100 to 240 VAC (50/60 Hz) |
| Power consumption | 60 Watts |
| Dimensions (D x W x H) | 48.9 cm D x 62.87 cm W x 68.58 cm H (19.25” D X 24.75” W X 27 H”) |
| Net weight | 59.7 Kg (131.6 lbs) |
| Shipping weight | 111.9 Kg (246.6 lbs) |
| Warranty | One-year limited warranty on workmanship and parts |
Consumables
| OsmoTECH HT | 96-well Plate-Based High-Throughput Micro Osmometer |
| SK-TECHHT Convenience Kit | Convenience Kit includes: • OsmoTECH HT Calibration and Verification Standard Set (3MA635) • OsmoTECH HT Cleaning Reel (635910) • OsmoTECH HT System Fluid (635934) • Clinitrol™ 290 (3MA029) • OsmoTECH HT 96 Well Plate Kit (635920) • Osmolality Linearity Set, 5-Level (3LA028) • Swab Cleaner Kit, Pkg 50 (202850) • OsmoTECH HT Micro-Sample Tubes, Pkg 1000 (HT1000) |
| Accessories | • Compatible dot matrix printer and cable (135022) • Printer paper (AN2TP5) • Barcode scanner (700056) |
Technical Service
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.
Advanced Instruments is the 65-year Global leader in osmolality testing with experience in developing and manufacturing analytical instruments. With a large install base across 90+ countries in North America, EMEA and Asia Pacific, the company is serving customers in three core markets: biopharma, clinical and food & beverage. Advanced Instruments is dedicated to increasing productivity and ensuring quality in the biopharma, clinical and food & beverage industries. With a focus on innovations that anticipate and overcome customer pain points, they help their customers deliver greater drug yields, better patient care, and ensure food safety.
More about Advanced Instruments: www.aicompanies.com/
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