OsmoTECH® HT Osmometer

A 96-well Plate-Based High-Throughput Micro Osmometer

The OsmoTECH HT, is a plate-based micro-osmometer to support the growing automation and high throughput needs in bioprocessing. The instrument ensures efficiency and acceleration of osmolality testing in for example cell line development and formulation development. The 21 CFR part 11 compliant OsmoTECH HT provides intuitive workflows and delivers unsurpassed data management.

Automation-friendly 96-well plate format
Supports 21 CFR part 11 and GMP
Reducing hands-on, automated cleaning
User friendly interface
OPC, USB, LIMS and network share connectivity
Flexible and secure data management

More osmometers:

For Biotech: Also check out out the OsmoTECH PRO multi-sample osmometer. Looking for a single-sample osmometer? Check out the OsmoTECH and OsmoTECH XT. For Clinical Chemisty: Also check out the OsmoPRO and OsmoPRO MAX multi-sample osmometer. Looking for a single-sample osmometer? Check out the Osmo1.

Learn more about osmolality

Cell Culture
Good manufacturing practice (GMP)
Automation
Process Development
Upstream
Downstream
Osmolality

Belgium
Denmark
Netherlands
Sweden

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OsmoTECH HT – Osmometer for high sample throughput

The OsmoTECH HT was developed to meet the high throughput needs of cell line development, clone screening, and early process development. It incorporates freezing point depression technology to test osmolality and offers accuracy, precision, and ease-of-use.

The OsmoTECH HT is an automation-friendly, batch plate-based osmometer that offers these features to streamline sample testing while ensuring data integrity in all phases of the testing process:

An easy-to-use, menu-driven touchscreen interface to access instrument features.
Automated sample pipetting from a 96-well plate format to support your high-volume workflow, eliminating the need for time-consuming manual pipetting into wells and ensuring pipetting consistency.
Reliable results using small sample sizes: Only 50 μL per plate well needed to run a standard sample test.
Load up to two plates onto the instrument to perform 192 consecutive tests. The instrument can perform up to 1,000 tests before consumables need to be reloaded.
Industry-standard support for interfacing with a local area network (LAN).
Automated barcode reading of 96-well plates.
Customized sampling templates.

Technical data

Sample type	Aqueous-based solution
Sample volume	Minimum per well: 50 μl Maximum per well: 180 μl
Test time	60 mins for 25 samples
	3 hr 40 mins for 96 well plate
Sample format	96-well plate
Resolution	1 mOsm/kg H₂O
Range (2)	0-2000 mOsm/kg H₂O
Accuracy (3) (AI standards and reference solutions)	Mean value ±3 mOsm/kg H₂O from nominal value between 0 and 400 mOsm/kg H₂O (1 SD) Mean value ±1% from nominal value greater than 400 to 2000 mOsm/kg H₂O (1 SD)
Within-run repeatability (3) (AI standards and reference solutions)	Standard deviation ≤3 mOsm/kg H₂O between 0 and 400 mOsm/kg H₂O Coefficient of variation ≤1% greater than 400 to 2000 mOsm/kg H₂O
Operating conditions	Temperature: 18 °C to 35 °C (64 °F to 95 °F) Humidity: 5 to 80% relative humidity (non-condensing)
Supported languages	Simple Chinese, English, French, German, Italian, Japanese, Korean, Portuguese, Russian, Spanish, Turkish
Storage temperature	-20 °C to +45 °C (-4 °F to +113 °F)
Electrical voltage	100 to 240 VAC (50/60 Hz)
Power consumption	60 Watts
Dimensions (D x W x H)	48.9 cm D x 62.87 cm W x 68.58 cm H (19.25” D X 24.75” W X 27 H”)
Net weight	59.7 Kg (131.6 lbs)
Shipping weight	111.9 Kg (246.6 lbs)
Warranty	One-year limited warranty on workmanship and parts

Downloads

Brochures

OsmoTECH HT Brochure

1.08 MB

Consumables

OsmoTECH HT	96-well Plate-Based High-Throughput Micro Osmometer
SK-TECHHT Convenience Kit	Convenience Kit includes: • OsmoTECH HT Calibration and Verification Standard Set (3MA635) • OsmoTECH HT Cleaning Reel (635910) • OsmoTECH HT System Fluid (635934) • Clinitrol™ 290 (3MA029) • OsmoTECH HT 96 Well Plate Kit (635920) • Osmolality Linearity Set, 5-Level (3LA028) • Swab Cleaner Kit, Pkg 50 (202850) • OsmoTECH HT Micro-Sample Tubes, Pkg 1000 (HT1000)
Accessories	• Compatible dot matrix printer and cable (135022) • Printer paper (AN2TP5) • Barcode scanner (700056)

Technical Service

During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.

Detailed information about our support options can be found here.

Advanced Instruments

Advanced Instruments is the 65-year Global leader in osmolality testing with experience in developing and manufacturing analytical instruments. With a large install base across 90+ countries in North America, EMEA and Asia Pacific, the company is serving customers in three core markets: biopharma, clinical and food & beverage. Advanced Instruments is dedicated to increasing productivity and ensuring quality in the biopharma, clinical and food & beverage industries. With a focus on innovations that anticipate and overcome customer pain points, they help their customers deliver greater drug yields, better patient care, and ensure food safety.

More about Advanced Instruments: www.aicompanies.com/