Advanced Instruments
OsmoTECH® PRO Osmometer
Multi-Sample Micro-Osmometer
The OsmoTECH® PRO from Advanced Instruments is the only multi-sample osmometer designed to support 21 CFR Part 11 compliance, and it offers flexibility to configure these features to your specific needs in Pharma Industry. It is equipped with a 20-position carousel for high sample throughput.
- Method: freezing point depression
- 20-position carousel
- 30 µl sample volume
- Support 21 CFR Part 11 compliance
- OPC connectivity
- Factory calibrated
More osmometers:
For a fully automated osmometer check out the new OsmoTECH HT (96-well plate, high through put) or the OsmoPRO MAX. Looking for a single-sample osmometer? Check out the OsmoTECH and OsmoTECH XT. Or a multi-sample osmometer for Clinical Chemistry? Check out the OsmoPRO and OsmoPRO MAX.
- Biopharmaceutical Quality Control
- Downstream
- Good manufacturing practice (GMP)
- Osmolality
- Process analytics technology (PAT)
- Upstream
- Cell Culture
- Cell Biology
- Biotechnology
- Process Control
- Belgium
- Denmark
- Netherlands
- Sweden
OsmoTECH® PRO – Multisample micro-osmometer
The OsmoTECH® PRO from Advanced Instruments is the only multi-sample osmometer designed to support 21 CFR Part 11 compliance, and it offers flexibility to configure these features to your specific needs in Pharma Industry. It is equipped with a 20-position carousel for high sample throughput. Osmolality testing can provide additional quality and efficiency throughout the bioproduction workflows. The method of freezing point depression is the industry standard and offers the highest precision and reliability, thus serving to optimize your quality control. The integrated barcode scanner simplifies personnel and sample identification.
With a sample volume of only 30 µl, the osmolality of samples can be determined serially within 90 seconds in the sample carousel. There are also several ways (including OPC, embedded web server, direct file transfer to a network folder and TCP/IP communication) to quickly transfer data from the device. This instrument provides a fast, accurate, and flexible method to check and monitor your bioprocess. The OsmoTECH® PRO is factory calibrated and ready to test!
Advanced Instruments | OsmoTECH PRO | Multi-Sample Micro-Osmometer
Technical data
Sample volume | 30 ±1 μL |
Sample type | Aqueous solution |
Test time | 90 seconds (typical) to test single sample |
40 minutes (typical) to test 20 samples | |
Sample capacity | Multi sample |
Resolution | 1 mOsm/kg H2O |
Range | 0-2000 mOsm/kg H2O |
Accuracy | Mean value ±3 mOsm/kg H2O from nominal value |
between 0 and 400 mOsm/kg H2O (1 SD) | |
Mean value ±0.75% from nominal value | |
between 400-2000 mOsm/kg H2O (1 SD) | |
Within-Run Repeatability3 | Standard deviation ≤3 mOsm/kg H2O between 0 and 400 mOsm/kg H2O |
Coefficient of variation ≤0.75% between 400 and 2000 mOsm/kg H2O | |
Temperature effects | Less than 1 mOsm/kg H2O per 5 °C (9 °F) ambient temperature change |
Supported languages | Chinese, English, French, German, Italian, Japanese, Korean, Russian, Spanish, Turkish |
Storage temperature | -20 °C to +45 °C |
Electrical voltage | 100 to 240 VAC (50/60 Hz) |
Power consumption | 60 Watts |
Dimensions (D x W x H) | 39 cm x 25 cm x 46 cm |
Net weight | 13.2 kg |
Shipping weight | 17.7 kg |
Consumables
AI-3MA000 | 0 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3MA005 | 50 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3LA011 | 100 mOsm CALIBRATION STANDARD 10x 5 mL | |
AI-3MA020 | 200 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3MA003 | 300 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3MA040 | 400 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3LA051 | 500 mOsm CALIBRATION STANDARD 10x 5 mL | |
AI-3MA085 | 850 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3LA091 | 900 mOsm CALIBRATION STANDARD 10x 5 mL | |
AI-3MA100 | 1000 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3LA151 | 1500 mOsm CALIBRATION STANDARD 10x 5 mL | |
AI-3MA200 | 2000 mOsm CALIBRATION STANDARD 10x 2 mL | |
AI-3MA028 | PROTINOL 3 LEVEL OSMOMETER CONTROL 9x 3 mL | |
AI-3MA029 | CLINITROL 290 REFERENCE SOLUTION 10x 2 mL | |
AI-3LA028 | OSMOLALITY LINEARITY SET 100-2000 mOsm/kg 5x 2x 5 ml | |
AI-222825 | DISPOSABLE SAMPLE TUBES 1x 500 | |
AI-222840 | PROBE WIPER RINGS 50 | |
AI-SK-TECHPRO | CONVENIENCE KIT | |
AI-800097 | PIPETTE TIPS - 10 PACKS OF 96 TIPS | |
AI-202850 | SWAB CLEANER KIT, PACKAGE OF 50 | |
Accessories | ||
AI-222005UG | OSMOTECH PRO USER’S GUIDE | |
AI-222006SM | OSMOTECH PRO SERVICE MANUAL | |
AI-222820 | 30-MICROLITER PIPET |
Technical Service
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.

Advanced Instruments is the 65-year Global leader in osmolality testing with experience in developing and manufacturing analytical instruments. With a large install base across 90+ countries in North America, EMEA and Asia Pacific, the company is serving customers in three core markets: biopharma, clinical and food & beverage. Advanced Instruments is dedicated to increasing productivity and ensuring quality in the biopharma, clinical and food & beverage industries. With a focus on innovations that anticipate and overcome customer pain points, they help their customers deliver greater drug yields, better patient care, and ensure food safety.
More about Advanced Instruments: www.aicompanies.com/
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